Evidence-Based Medicine
By May 2025, 60 articles have been published in domestic and in foreign journals, including 13 SCI articles, with a total impact factor of 107+.
This study found that needle-free insulin injection (NFII) significantly improved fasting glucose variability and reduced basal insulin needs compared to conventional pens in type 2 diabetes patients. The results suggest NFII enhances insulin absorption, providing more stable glucose control and potential benefits for diabetes management.
Key Words
Needle-free Injection, Glocuse Control, Diabetes Management
This study found that needle-free jet injection of insulin glargine improved glycemic control in type 2 diabetes patients, lowering postprandial glucose and reducing the risk of hyperglycemia compared to conventional pens.
Key Words
Needle-free Jet Injection, Glycemic Control
This study found that using a needle-free jet injector for insulin glargine in type 2 diabetes patients lowered 24-hour mean glucose, reduced preprandial glucose, and minimized hypoglycemia compared to conventional pens. It also decreased basal insulin requirements, suggesting potential benefits for both glucose management and treatment costs.
Key Words
Insulin Delivery, Glucose Management, Insulin Glargine
This study found that needle-free injectors in Chinese patients with type 2 diabetes significantly reduced insulin dosage needs, adverse reactions, and injection-related fear, supporting better patient compliance. The results suggest needle-free injectors may offer advantages over conventional pens, providing safer and more effective long-term diabetes management.
Key Words
Insulin Therapy, Patient Compliance, Injection Safety
This study found that jet injectors improved postprandial glucose control and insulin levels in type 2 diabetes patients compared to insulin pens. Patients also preferred jet injectors due to less pain and tissue injury, supporting their potential as a superior insulin delivery method.
Key Words
Jet Injectors, Glucose Control, Insulin Pen
This 16-week clinical trial found that needle-free insulin injectors (NFII) were as effective as conventional insulin pens in controlling blood glucose in type 2 diabetes patients, while providing higher patient satisfaction. NFII also showed fewer skin-related adverse effects, suggesting it may improve adherence and overall diabetes management.
Key Words
Insulin Injectors, Patient Satisfaction, Type 2 Diabetes
This study found that needle-free insulin syringes effectively controlled fasting blood glucose in early-onset type 2 diabetes patients while causing less pain and fewer skin reactions than conventional pens. The findings suggest they may improve patient well-being, compliance, and overall diabetes management.
Key Words
Fasting Blood Glocuse, Diabetes Treatment
This study found that needle-free injection (NFI) reduced psychological insulin resistance, improved treatment adherence, and allowed for lower insulin doses while maintaining glycemic control in type 2 diabetes patients. It also lessened pain and injection-site reactions without increasing hypoglycemia, supporting NFI as a safer and more effective insulin delivery method.
Key Words
Treatment Compliance, Insulin Resistance, Type 2 Diabetes
This study found that needle-free injections provided better fasting and post-breakfast glucose control, reduced daily fluctuations, and required lower fast-acting insulin doses compared to needle-based injections in hospitalized type 2 diabetes patients. Patients also reported less pain, suggesting needle-free injections may offer both improved glycemic management and greater comfort during intensive insulin therapy.
Key Words
Patient Comfort, Glycemic Control, Painless Injection
This study found that insulin aspart absorption with needle-free injections did not differ across the abdomen, upper arm, or thigh, and was not affected by skin thickness. These results suggest that injection sites do not influence insulin absorption, supporting flexibility in rotating injection sites for patients using needle-free insulin delivery.
Key Words
Diabetes Management, Insulin Aspart, Glycemic Control
This study found that the QS-M needle-free jet injector delivered insulin lispro with faster absorption and a stronger early glucose-lowering effect than conventional pens, closely mimicking natural insulin secretion. Despite the quicker action, overall insulin exposure was similar, and no local adverse reactions were observed, supporting its effectiveness and safety.
Key Words
Insulin Lispro, Glucose-lowering Effect
This study found that using a needle-free jet injector for insulin glargine in type 2 diabetes patients lowered 24-hour mean glucose, reduced preprandial glucose, and minimized hypoglycemia compared to conventional pens. It also decreased basal insulin requirements, suggesting potential benefits for both glucose management and treatment costs.
Key Words
Insulin Delivery, Glucose Management, Insulin Glargine
This study showed that needle-free injection (NFI) of mRNA-LNP COVID-19 vaccines produced stronger immune responses, with higher neutralizing antibody levels, than traditional needle injection. NFI also reduced pain, maintained vaccine stability, allowed flexible administration routes, and supported split-dose delivery, making it a safe and effective alternative for vaccination.
Key Words
Needle-free Injecion, COVID-19 Vaccine, Immune Response
This study found that combining needle-free injection technology with midazolam nanosuspension enabled faster drug absorption, reduced tissue injury, and maintained drug stability. The approach also improved bioavailability and sustained therapeutic effects, suggesting a safer and more effective method for intramuscular delivery of poorly soluble drugs.
Key Words
Drug Absorption, Midazolam, Intramuscular Injection
This study found that needle-free insulin injection (NFII) significantly improved fasting glucose variability and reduced basal insulin needs compared to conventional pens in type 2 diabetes patients. The results suggest NFII enhances insulin absorption, providing more stable glucose control and potential benefits for diabetes management.
Key Words
Needle-free Injection, Glocuse Control, Diabetes Management
This study found that needle-free jet injection of insulin glargine improved glycemic control in type 2 diabetes patients, lowering postprandial glucose and reducing the risk of hyperglycemia compared to conventional pens.
Key Words
Needle-free Jet Injection, Glycemic Control
This study found that using a needle-free jet injector for insulin glargine in type 2 diabetes patients lowered 24-hour mean glucose, reduced preprandial glucose, and minimized hypoglycemia compared to conventional pens. It also decreased basal insulin requirements, suggesting potential benefits for both glucose management and treatment costs.
Key Words
Insulin Delivery, Glucose Management, Insulin Glargine
This study found that needle-free injectors in Chinese patients with type 2 diabetes significantly reduced insulin dosage needs, adverse reactions, and injection-related fear, supporting better patient compliance. The results suggest needle-free injectors may offer advantages over conventional pens, providing safer and more effective long-term diabetes management.
Key Words
Insulin Therapy, Patient Compliance, Injection Safety
This study found that jet injectors improved postprandial glucose control and insulin levels in type 2 diabetes patients compared to insulin pens. Patients also preferred jet injectors due to less pain and tissue injury, supporting their potential as a superior insulin delivery method.
Key Words
Jet Injectors, Glucose Control, Insulin Pen
This 16-week clinical trial found that needle-free insulin injectors (NFII) were as effective as conventional insulin pens in controlling blood glucose in type 2 diabetes patients, while providing higher patient satisfaction. NFII also showed fewer skin-related adverse effects, suggesting it may improve adherence and overall diabetes management.
Key Words
Insulin Injectors, Patient Satisfaction, Type 2 Diabetes
This study found that needle-free insulin syringes effectively controlled fasting blood glucose in early-onset type 2 diabetes patients while causing less pain and fewer skin reactions than conventional pens. The findings suggest they may improve patient well-being, compliance, and overall diabetes management.
Key Words
Fasting Blood Glocuse, Diabetes Treatment
This study found that needle-free injection (NFI) reduced psychological insulin resistance, improved treatment adherence, and allowed for lower insulin doses while maintaining glycemic control in type 2 diabetes patients. It also lessened pain and injection-site reactions without increasing hypoglycemia, supporting NFI as a safer and more effective insulin delivery method.
Key Words
Treatment Compliance, Insulin Resistance, Type 2 Diabetes
This study found that needle-free injections provided better fasting and post-breakfast glucose control, reduced daily fluctuations, and required lower fast-acting insulin doses compared to needle-based injections in hospitalized type 2 diabetes patients. Patients also reported less pain, suggesting needle-free injections may offer both improved glycemic management and greater comfort during intensive insulin therapy.
Key Words
Patient Comfort, Glycemic Control, Painless Injection
This study found that insulin aspart absorption with needle-free injections did not differ across the abdomen, upper arm, or thigh, and was not affected by skin thickness. These results suggest that injection sites do not influence insulin absorption, supporting flexibility in rotating injection sites for patients using needle-free insulin delivery.
Key Words
Diabetes Management, Insulin Aspart, Glycemic Control
This study found that the QS-M needle-free jet injector delivered insulin lispro with faster absorption and a stronger early glucose-lowering effect than conventional pens, closely mimicking natural insulin secretion. Despite the quicker action, overall insulin exposure was similar, and no local adverse reactions were observed, supporting its effectiveness and safety.
Key Words
Insulin Lispro, Glucose-lowering Effect
This study found that using a needle-free jet injector for insulin glargine in type 2 diabetes patients lowered 24-hour mean glucose, reduced preprandial glucose, and minimized hypoglycemia compared to conventional pens. It also decreased basal insulin requirements, suggesting potential benefits for both glucose management and treatment costs.
Key Words
Insulin Delivery, Glucose Management, Insulin Glargine
This study showed that needle-free injection (NFI) of mRNA-LNP COVID-19 vaccines produced stronger immune responses, with higher neutralizing antibody levels, than traditional needle injection. NFI also reduced pain, maintained vaccine stability, allowed flexible administration routes, and supported split-dose delivery, making it a safe and effective alternative for vaccination.
Key Words
Needle-free Injecion, COVID-19 Vaccine, Immune Response
This study found that combining needle-free injection technology with midazolam nanosuspension enabled faster drug absorption, reduced tissue injury, and maintained drug stability. The approach also improved bioavailability and sustained therapeutic effects, suggesting a safer and more effective method for intramuscular delivery of poorly soluble drugs.
Key Words
Drug Absorption, Midazolam, Intramuscular Injection